exo-3-Cbz-3-azabicyclo[3.1.0]hexane-6-carboxylic acid 97%

rel-(1R,5S,6s)-3-Boc-3-azabicyclo[3.1.0]hexane-6-carboxylic acid (CAS 1401464-07-0) is supplied by Activate Scientific.This Boc-protected, cyclopropane-fused pyrrolidine bears a free carboxylic acid at the C6 bridge position in the endo configuration. As a rigid proline/pyrrolidine bioisostere, the ring locks the relative orientation of the nitrogen and the C6 substituent; the endo/exo relationship of the acid can meaningfully affect binding-pocket presentation, making both diastereomers useful, independent SAR tools. The free acid supports standard amide coupling chemistry.Buy rel-(1R,5S,6s)-3-Boc-3-azabicyclo[3.1.0]hexane-6-carboxylic acid from Activate Scientific online today. Every product in the Activate Scientific portfolio undergoes rigorous quality control testing, and our building blocks are supplied to the highest purity standards. Activate Scientific also offers custom synthesis via our quote tool.

exo-3-Boc-3-azabicyclo[3.1.0]hexane-6-carboxylic acid (CAS 927679-54-7) is supplied by Activate Scientific.This is the exo diastereomer of the Boc-protected, cyclopropane-fused pyrrolidine-6-carboxylic acid, differing from its endo counterpart in the spatial orientation of the acid relative to the bicyclic ring system. Both endo and exo isomers are commonly prepared and evaluated in parallel during SAR studies built around this scaffold, since the stereochemical difference can meaningfully change target engagement.Buy exo-3-Boc-3-azabicyclo[3.1.0]hexane-6-carboxylic acid from Activate Scientific online today. Every product in the Activate Scientific portfolio undergoes rigorous quality control testing, and our building blocks are supplied to the highest purity standards. Activate Scientific also offers custom synthesis via our quote tool.