Cyclopentane
- High-purity Cyclopentane
- Extensive range of Cyclopentane
- Ideal for drug discovery applications and organic synthesis
- Fast delivery and expert support
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(1S,3R)-1-(Acetoxy)-3-hydroxycyclopentane 95%EE
(-)-(1R,3S)-N-Fmoc-3-aminocyclopentanecarboxylic acid 97%EE
(-)-Camphoric acid 98%
(1-Aminocyclopentyl)methanol HCl 97%
(1-Aminocyclopentyl)methanol Oxalate 95%
(1-Cyclopentyl-1H-imidazol-5-yl)methanol 95%
(1-Cyclopentyl-1H-pyrazol-3-yl)acetic Acid 95%
(1-Cyclopentyl-1H-pyrazol-3-yl)acetonitrile 95%
(1-Cyclopentyl-1H-pyrazol-3-yl)methanol 95%
(1-Cyclopentyl-1H-pyrazol-5-yl)acetonitrile 95%
(1-Cyclopentyl-1H-pyrazol-5-yl)methanol 95%
(1-Cyclopentyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)boronic acid 95%
(1-Cyclopentyl-3-oxo-2-piperazinyl)acetic Acid 95%
(1-Cyclopentyl-4-methyl-1H-imidazol-2-yl)methanol 95%
(1-Cyclopentylcyclopropyl)amine HCl 95%
(1-Fluorocyclopentyl)methanamine 97%
(1-Fluorocyclopentyl)methanol 95%
(1-Methylcyclopentyl)methanamine HCl 97%
(1-Methylcyclopentyl)methanol 97%
(1-Phenylcyclopentyl)methanol 97%
(1R, 2R)-1-(Boc-amino)-2-hydroxy-2-methyl-cyclopentane 95%
(1R, 2R)-2-Amino-1-methyl-cyclopentanol HCl 95%
(1R,2R)-1-(Boc-amino)-2-aminocyclopentane 97%EE
(1R,2R)-1-(Boc-amino)cyclopentane-2-carboxylic acid 97%EE
Understanding Cyclopentane in Modern Chemistry
Explore the critical role of Cyclopentane in pharmaceutical development, medicinal chemistry research and organic chemistry.
Precision Chemistry
Advanced synthesis techniques for superior quality compounds
Great Molecules for Chemical Diversity
Our catalogue of building blocks contains a diverse range of highly functionalised and decorated compounds. The 20 years of experience in supplying cutting-edge building blocks have given us the expertise to bring you the most exciting chemical motifs, adding chemical diversity to your projects.
Our diverse catalogue is tailored for medicinal chemistry, small molecule drug discovery and organic synthesis. Our unique range of Cyclopentane adds value to any research project.
We constantly add to our catalogue; the latest additions include a range of new Cyclopentane. We continue to bring you the latest and most exciting chemical compounds.
Quality Assurance
Every Cyclopentane product in our portfolio undergoes rigorous quality control testing. Our building blocks are supplied with the highest purity standards. We provide complete analytical characterisation, including:
- ¹H and ¹³C NMR spectroscopy for structural verification
- HPLC chromatograms confirming purity levels
- Certificate of Analysis available.
- Standard purity of 95%
- Specific purity available upon request.
Diverse Applications
From oncology to neuroscience, enabling next-generation therapeutics
Cyclopentane products in our portfolio
The cyclopentane ring occupies a well-established position in small-molecule drug discovery, drawing much of its value from its prevalence across bioactive natural products and its structural similarity to the ribose sugar found in nucleosides. The cyclopentane motif has been utilised as an effective core scaffold for several highly successful medicinal chemistry programmes, providing underappreciated yet significant value for biomedical research. Unlike more strained carbocycles, cyclopentane adopts a low-strain pseudo-envelope conformation that reduces torsional penalties, supports multiple stereocentres, and presents substituents with well-defined directionality. These properties make it well suited to conformational restriction strategies, where locking a flexible acyclic chain or replacing a metabolically labile group can sharpen target engagement and improve selectivity.
Across therapeutic areas, cyclopentane has found application in antiviral, cardiovascular, oncology, and immunology programmes, including as a carbocyclic mimic of the ribose ring in nucleoside analogues and as a hydrophobic pocket-filling element in kinase inhibitors. Ticagrelor (Brilinta, AstraZeneca), a direct-acting P2Y12 receptor antagonist in the cyclopentyltriazolopyrimidine chemical class, was approved by the FDA in July 2011 as the first reversibly binding oral ADP receptor antagonist for the reduction of cardiovascular death and myocardial infarction in patients with acute coronary syndrome. Deuruxolitinib (Leqselvi, Sun Pharma), approved by the FDA in July 2024 for the treatment of severe alopecia areata in adults, is an oral JAK1 and JAK2 inhibitor in which selective deuteration of the cyclopentyl ring significantly improves pharmacokinetic properties relative to ruxolitinib.
Our range of cyclopentanes features novel substitutions and the incorporation of synthetically tractable functional groups such as boronic acids and esters, amines, carboxylic acids, ketones, hydroxyls and halogens to enable expedient synthetic strategies.
Please examine a selection of cyclopentanes in our catalogue. The full range can be found using the substructure feature of our Search tools.
Frequently Asked Questions
Common questions about our Cyclopentane products.
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