Better Building Blocks for Drug Discovery

We offer an extensive range of over 140,000 building blocks and chemical reagents including heterocycles, amino acids, boronic acids, PEG linkers, fluorinated compounds, spiro compounds, cycloalkyls, alkynes, azides, bicyclic rings, catalysts and many more specialised compounds for, organic chemistry, pharmaceutical research and drug discovery.

It is our top priority to provide high purity products to our customers. Our products are supplied with a standard purity of 95%, many with >98% or >99%. Each batch is verified through state-of-the-art analytical methods (NMR, HPLC, LC-MS) and documented with a Certificate of Analysis (CoA). Specific purity available upon request.

95% of our catalogue products are in stock, with delivery worldwide within 5 working days. Our experienced chemists ensure that for custom synthesis projects, typical delivery times range from 2-8 weeks with superior success rates.

Yes, we provide professional custom synthesis services for tailored chemical compounds. Our experienced team of chemists can synthesise complex molecules from milligram to kilogram quantities. We specialise in organic synthesis, amino synthesis, heterocyclic chemistry, fluorine chemistry, boronic acid derivatives, and chiral synthesis.

Our product purity is validated by our QC department, with a Certificate of Analysis (CoA) available for all purchased material.  Purity is determined by NMR spectra (¹H-NMR, ¹³C-NMR), HPLC chromatograms, mass spectrometry (MS/LC-MS) data. The enantiomeric excess of chiral compounds is determined by optical rotation or chiral HPLC.

Absolutely. Our service supports projects from process development to pilot production. We can produce compounds in quantities ranging from milligrams for initial screening to kilograms for preclinical and clinical studies. We can support you through the drug discovery process at all scales. We optimize synthetic routes for maximum yield, minimum cost, and improved sustainability.

We deliver building blocks and reagents worldwide with complete documentation for international shipping from our offices in Germany and the UK. Our experienced logistics department handles all regulatory requirements, dangerous goods documentation, and customs paperwork. We have local inventory in Germany and the UK for faster delivery.

We offer an advanced structure search tool powered by Marvin JS technology that allows you to search by molecular structure, substructure, and similarity. You can draw your target structure directly in the browser and find exact matches, similar compounds, or building blocks containing specific substructures. You can also search our catalogue using compound ID, name, CAS and SMILES code.

Yes, our catalogue supports CAS number based searching. Our search tools allow you to search using:

•  Chemical name
• CAS number 
• Compound ID (AS number) 
• MDL Number  
• SMILES 
• InChI

We also offer structure search. Our search tools offer Substructure search, Exact structure and Similarity search. This allows you to find the product you want as quickly and easily as possible. Our quick and easy-to-use search tools help you save time when looking for chemicals. The similarity and structure search helps you easily find great alternatives if we do not have the material you are looking for.

Yes, our chemical building blocks are specifically designed for pharmaceutical research and drug discovery. They are used by all big pharmaceutical companies, biotechnology firms, and academic research institutions worldwide for applications including drug discovery, lead optimisation, fragment-based drug design, and chemical biology.

Yes, we work under strict confidential non-disclosure agreements (NDAs) for all custom synthesis projects. We protect your intellectual property throughout the entire project and maintain complete confidentiality regarding your compound structures, research goals, and project details.

Our products are used in diverse research areas including drug discovery and lead optimization, fragment-based drug design (FBDD), chemical biology and probe development, agrochemical research, materials science, peptide and protein conjugation, bioconjugation, click chemistry, and medicinal chemistry research across various therapeutic areas.

Yes, the catalogue includes PEG linkers, alkyl linkers, and functional building blocks commonly used in PROTAC design, including amine and carboxylic acid termini for coupling to both the target ligand and the E3 ligase binder. The linker catalogue alone contains over 400 PEG linker products at high purity. In addition to our linkers, we also offer CRBN ligands and VHL ligands. We have established a robust library of pre-formed E3-ligand linker intermediates. This resource enables the efficient synthesis of a wide array of diverse PROTAC candidates, facilitating their rapid evaluation and optimisation for targeted protein degradation applications.