PEG linkers are highly attractive as linker molecules due to their low immunogenicity, lack of toxicity and water solubility. They are commonly attached to peptides, antibody fragments and proteins altering the physiochemical properties. PEGylation can also give several pharmacological advantages including; increased solubility, increased stability, reduced dosage frequency and extended circulated life. This has led to a wide variety of PEGylated pharmaceuticals across a range of therapeutic areas: Plegridy US7588755B1 (Biogen) for treatment of multiple sclerosis, Pegvaliase US20190376081 (BioMarin) for treatment of genetic disease phenylketonuria, Peginesatide US7084245B2 (Affymax) for treatment of anaemia associated with chronic kidney disease. PEGylation also has biotech uses for cell transfection and gene editing in non-human cells. Please examine a sample of our PEG linkers.
PEG linkers are highly attractive as linker molecules due to their low immunogenicity, lack of toxicity and water solubility. They are commonly attached to peptides, antibody fragments and proteins... read more »
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PEG linkers are highly attractive as linker molecules due to their low immunogenicity, lack of toxicity and water solubility. They are commonly attached to peptides, antibody fragments and proteins altering the physiochemical properties. PEGylation can also give several pharmacological advantages including; increased solubility, increased stability, reduced dosage frequency and extended circulated life. This has led to a wide variety of PEGylated pharmaceuticals across a range of therapeutic areas: Plegridy US7588755B1 (Biogen) for treatment of multiple sclerosis, Pegvaliase US20190376081 (BioMarin) for treatment of genetic disease phenylketonuria, Peginesatide US7084245B2 (Affymax) for treatment of anaemia associated with chronic kidney disease. PEGylation also has biotech uses for cell transfection and gene editing in non-human cells. Please examine a sample of our PEG linkers.
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AS95786-MG100 Methyl...
Catalog # AS95786 Formula: C10H22ClNO6 Mass: 287.74 C.A.S. / related C.A.S: [2173992-41-9] / [] MDL: MFCD31567430 Appearance: solid Colour: clear Hazardous Classification: Warning Storage Temp: 2-7°C Refrigerate logP: pKa: Tariff Code:...
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AS118401-MG250 2,2-Dimethyl-4-oxo-3,8,11,14,17,20-hexaoxa-5-az...
Catalog # AS118401 Formula: C18H35NO9 Mass: 409.47 C.A.S. / related C.A.S: [1347750-78-0] / [] MDL: MFCD24539478 Appearance: liquid Colour: clear Hazardous Classification: Corrosive Storage Temp: 2-7°C Refrigerate logP: pKa: Tariff Code:...
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AS118354-MG250 2,5,8,11-Tetraoxatridecan-13-yl...
Catalog # AS118354 Formula: C16H26O7S Mass: 362.44 C.A.S. / related C.A.S: [62921-76-0] / [] MDL: MFCD11041134 Appearance: powder or crystals Colour: white to yellow Hazardous Classification: Warning Storage Temp: 2-7°C Refrigerate logP:...
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AS118042-MG100 HO-PEG4-CH2COOtBu 97+%
Catalog # AS118042 Formula: C14H28O7 Mass: 308.37 C.A.S. / related C.A.S: [169751-72-8] / [] MDL: MFCD27635170 Appearance: solid Colour: yellow to brown Hazardous Classification: Warning Storage Temp: 2-7°C Refrigerate logP: pKa: Tariff...
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AS117863-MG100 Fmoc-N-Amido-PEG8-acid 97+%
Catalog # AS117863 Formula: C34H49NO12 Mass: 663.75 C.A.S. / related C.A.S: [756526-02-0] / [] MDL: MFCD11041143 Appearance: liquid Colour: light yellow to yellow Hazardous Classification: Warning Storage Temp: -20°C Freezer logP: pKa:...
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AS117864-MG100 FMOC-PEG9-CH2CH2COOH 97+%
Catalog # AS117864 Formula: C36H53NO13 Mass: 707.80 C.A.S. / related C.A.S: [1191064-81-9] / [] MDL: MFCD28385470 Appearance: liquid Colour: clear Hazardous Classification: Warning Storage Temp: -20°C Freezer logP: pKa: Tariff Code:...
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AS117868-MG250 Fmoc-NH-PEG10-CH2CH2COOH 97+%
Catalog # AS117868 Formula: C38H57NO14 Mass: 751.86 C.A.S. / related C.A.S: [2101563-45-3] / [] MDL: MFCD28122954 Appearance: liquid Colour: clear Hazardous Classification: Warning Storage Temp: -20°C Freezer logP: pKa: Tariff Code:...
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AS117461-MG100 2-(2-(2-(2-(Nitrooxy)ethoxy)ethoxy)ethoxy)ethyl...
Catalog # AS117461 Formula: C15H23NO9S Mass: 393.41 C.A.S. / related C.A.S: [1973503-48-8] / [] MDL: MFCD30342473 Appearance: solid Colour: light yellow to yellow Hazardous Classification: Flammable Solids Storage Temp: 2-7°C Refrigerate...
245.00 € *
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AS116846-MG250 4,7,10,13-Tetraoxahexadecane-1,16-dioic acid 97+%
Catalog # AS116846 Formula: Mass: 294.13 C.A.S. / related C.A.S: [31127-85-2] / [] MDL: MFCD22201545 Appearance: solid or viscous liquid Colour: white to yellow Hazardous Classification: Corrosive Storage Temp: 2-7°C Refrigerate logP:...
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AS116747-MG250 tert-Butyl...
Catalog # AS116747 Formula: C17H36N2O7 Mass: 380.48 C.A.S. / related C.A.S: [189209-27-6] / [] MDL: MFCD22056313 Appearance: liquid Colour: pale yellow Hazardous Classification: Warning Storage Temp: 2-7°C Refrigerate logP: pKa: Tariff...
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AS116748-MG250 mPEG3-CH2CH2COOH 97+%
Catalog # AS116748 Formula: C10H20O6 Mass: 236.26 C.A.S. / related C.A.S: [67319-28-2] / [] MDL: MFCD11041124 Appearance: liquid Colour: clear Hazardous Classification: Warning Storage Temp: -20°C Freezer logP: pKa: Tariff Code: 39072011...
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AS115598-MG250 4,7,10,13-Tetraoxahexadecane-1,16-dinitrile 98+%
Catalog # AS115598 Formula: C12H20N2O4 Mass: 256.30 C.A.S. / related C.A.S: [57741-46-5] / [] MDL: MFCD00483880 Appearance: liquid Colour: clear Hazardous Classification: Toxic Storage Temp: 2-7°C Refrigerate logP: pKa: Tariff Code:...
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