One of the most exciting additions to our catalogue is a broad range of Alkynes. Alkynes are a structural feature present across a wide range of therapeutic areas including the antiretroviral Efavirenz –US91018192B2 (Gilead) for the treatment of HIV infection and the antifungal Terbinafinen WO2010086723A1 (Galderma). Alkynes are also found in antitumor drugs, with molecules containing the ene-diyne structure acting as highly aggressive antitumor drugs generating radical intermediates that attack the DNA of the tumour. Alkynes are a structural feature used in drug discovery for its participation in the Huisgen azide−alkyne 1,3-dipolar cycloaddition reaction, an example of ‘click chemistry’. As well as being incredibly useful for synthetic chemistry ‘click chemistry’ is frequently used in bioconjugation and can be used to attach fluorophores and other reporter molecules to biomolecules. Please examine a sample of our Alkynes. The full range of Alkynes can be viewed by using our class search tool.
One of the most exciting additions to our catalogue is a broad range of Alkynes. Alkynes are a structural feature present across a wide range of therapeutic areas including the antiretroviral... read more »
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One of the most exciting additions to our catalogue is a broad range of Alkynes. Alkynes are a structural feature present across a wide range of therapeutic areas including the antiretroviral Efavirenz –US91018192B2 (Gilead) for the treatment of HIV infection and the antifungal Terbinafinen WO2010086723A1 (Galderma). Alkynes are also found in antitumor drugs, with molecules containing the ene-diyne structure acting as highly aggressive antitumor drugs generating radical intermediates that attack the DNA of the tumour. Alkynes are a structural feature used in drug discovery for its participation in the Huisgen azide−alkyne 1,3-dipolar cycloaddition reaction, an example of ‘click chemistry’. As well as being incredibly useful for synthetic chemistry ‘click chemistry’ is frequently used in bioconjugation and can be used to attach fluorophores and other reporter molecules to biomolecules. Please examine a sample of our Alkynes. The full range of Alkynes can be viewed by using our class search tool.
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AS96002-MG100 (2,2-Dimethylbut-3-yn-1-yl)benzene 95+%
Catalog # AS96002 Formula: C12H14 Mass: 158.24 C.A.S. / related C.A.S: [65108-28-3] / [] MDL: MFCD25965789 Appearance: solid Colour: clear Hazardous Classification: Warning Storage Temp: 2-7°C Refrigerate logP: pKa: Tariff Code: 29420000...
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AS95915-MG100 Ethyl 3-(oxetan-3-yl)prop-2-ynoate 95+%
Catalog # AS95915 Formula: C8H10O3 Mass: 154.16 C.A.S. / related C.A.S: [2138167-54-9] / [] MDL: MFCD31463530 Appearance: solid Colour: clear Hazardous Classification: Toxic Storage Temp: 2-7°C Refrigerate logP: pKa: Tariff Code:...
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AS95719-G1 (2S)-But-3-yn-2-ol 97+% ee
Catalog # AS95719 Formula: C4H6O Mass: 70.09 C.A.S. / related C.A.S: [2914-69-4] / [] MDL: MFCD00190166 Appearance: liquid Colour: clear Hazardous Classification: Toxic Storage Temp: 2-7°C Refrigerate logP: pKa: Dangerous Goods in...
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AS95722-G1 tert-butyl N-[(2R)-But-3-yn-2-yl]carbamate 97+%
Catalog # AS95722 Formula: C9H15NO2 Mass: 169.22 C.A.S. / related C.A.S: [118080-82-3] / [] MDL: MFCD18831560 Appearance: solid Colour: white to yellow Hazardous Classification: Warning Storage Temp: 2-7°C Refrigerate logP: pKa: Tariff...
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AS95724-G25 But-3-yn-2-ol 97+%
Catalog # AS95724 Formula: C4H6O Mass: 70.09 C.A.S. / related C.A.S: [2028-63-9] / [] MDL: MFCD00004541 Appearance: liquid Colour: clear Hazardous Classification: Flammable Liquid Storage Temp: 2-7°C Refrigerate logP: pKa: Tariff Code:...
From 76.00 € *
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AS95494-MG100 1-Boc-4-ethynyl-4-fluoropiperidine 95+%
Catalog # AS95494 Formula: C12H18FNO2 Mass: 227.28 C.A.S. / related C.A.S: [191327-86-3] / [] MDL: MFCD23106422 Appearance: solid Colour: clear Hazardous Classification: Warning Storage Temp: 2-7°C Refrigerate logP: pKa: Tariff Code:...
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AS95456-G1 3-Ethynylimidazo[1,2-a]pyrazine 95+%
Catalog # AS95456 Formula: C8H5N3 Mass: 143.15 C.A.S. / related C.A.S: [943320-47-6] / [] MDL: MFCD17016048 Appearance: solid Colour: clear Hazardous Classification: Warning Storage Temp: 2-7°C Refrigerate logP: pKa: Tariff Code:...
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AS118536-MG250 1,2-Bis(4-fluorophenyl)ethyne 97+%
Catalog # AS118536 Formula: C14H8F2 Mass: 214.21 C.A.S. / related C.A.S: [5216-31-9] / [] MDL: MFCD01596894 Appearance: solid Colour: clear Hazardous Classification: Warning Storage Temp: 2-7°C Refrigerate logP: pKa: Tariff Code:...
From 121.00 € *
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AS118457-G1 3-(Trimethylsilyl)propiolic acid 97+%
Catalog # AS118457 Formula: C6H10O2Si Mass: 142.23 C.A.S. / related C.A.S: [5683-31-8] / [] MDL: MFCD00190216 Appearance: crystal -powder Colour: white - very pale yellow Hazardous Classification: Corrosive Storage Temp: 2-7°C...
From 141.00 € *
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AS118472-G1 3,7-Dimethyloct-6-en-1-yn-3-ol 97+%
Catalog # AS118472 Formula: C10H16O Mass: 152.23 C.A.S. / related C.A.S: [29171-20-8] / [] MDL: MFCD00129075 Appearance: liquid Colour: clear Hazardous Classification: Warning Storage Temp: 2-7°C Refrigerate logP: pKa: Tariff Code:...
From 19.00 € *
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AS118400-MG25 4-(Prop-1-yn-1-yl)benzoic acid 97+%
Catalog # AS118400 Formula: C10H8O2 Mass: 160.17 C.A.S. / related C.A.S: [223562-52-5] / [] MDL: MFCD18826068 Appearance: solid Colour: white to off-white Hazardous Classification: Corrosive Storage Temp: 2-7°C Refrigerate logP: pKa:...
From 125.00 € *
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AS118407-MG25 4-Ethynyl-2-fluorobenzoic acid 97+%
Catalog # AS118407 Formula: C9H5FO2 Mass: 164.13 C.A.S. / related C.A.S: [736117-41-2] / [] MDL: MFCD18826154 Appearance: solid Colour: clear Hazardous Classification: Corrosive Storage Temp: 2-7°C Refrigerate logP: pKa: Tariff Code:...
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