One of the most exciting additions to our catalogue is a broad range of Alkynes. Alkynes are a structural feature present across a wide range of therapeutic areas including the antiretroviral Efavirenz –US91018192B2 (Gilead) for the treatment of HIV infection and the antifungal Terbinafinen WO2010086723A1 (Galderma). Alkynes are also found in antitumor drugs, with molecules containing the ene-diyne structure acting as highly aggressive antitumor drugs generating radical intermediates that attack the DNA of the tumour. Alkynes are a structural feature used in drug discovery for its participation in the Huisgen azide−alkyne 1,3-dipolar cycloaddition reaction, an example of ‘click chemistry’. As well as being incredibly useful for synthetic chemistry ‘click chemistry’ is frequently used in bioconjugation and can be used to attach fluorophores and other reporter molecules to biomolecules. Please examine a sample of our Alkynes. The full range of Alkynes can be viewed by using our class search tool.
One of the most exciting additions to our catalogue is a broad range of Alkynes. Alkynes are a structural feature present across a wide range of therapeutic areas including the antiretroviral... read more »
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One of the most exciting additions to our catalogue is a broad range of Alkynes. Alkynes are a structural feature present across a wide range of therapeutic areas including the antiretroviral Efavirenz –US91018192B2 (Gilead) for the treatment of HIV infection and the antifungal Terbinafinen WO2010086723A1 (Galderma). Alkynes are also found in antitumor drugs, with molecules containing the ene-diyne structure acting as highly aggressive antitumor drugs generating radical intermediates that attack the DNA of the tumour. Alkynes are a structural feature used in drug discovery for its participation in the Huisgen azide−alkyne 1,3-dipolar cycloaddition reaction, an example of ‘click chemistry’. As well as being incredibly useful for synthetic chemistry ‘click chemistry’ is frequently used in bioconjugation and can be used to attach fluorophores and other reporter molecules to biomolecules. Please examine a sample of our Alkynes. The full range of Alkynes can be viewed by using our class search tool.
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AS97099-G1 N,N-Diethyl-5-[2-(3-fluorophenyl)ethynyl]pyridi...
Catalog # AS97099 Formula: C18H17FN2O Mass: 296.34 C.A.S. / related C.A.S: [1946021-40-4] / [] MDL: MFCD30146434 Appearance: solid Colour: clear Hazardous Classification: Warning Storage Temp: 2-7°C Refrigerate logP: pKa: Tariff Code:...
1,362.00 € *
NEW
AS97102-MG100 trans-4-Ethynylcyclohexan-1-ol 95+%
Catalog # AS97102 Formula: C8H12O Mass: 124.18 C.A.S. / related C.A.S: [1346526-64-4] / [] MDL: MFCD22381567 Appearance: liquid Colour: clear Hazardous Classification: Corrosive Storage Temp: 2-7°C Refrigerate logP: pKa: Tariff Code:...
From 288.00 € *
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AS96944-G1 2-Ethynyloxetane 95+%
Catalog # AS96944 Formula: C5H6O Mass: 82.10 C.A.S. / related C.A.S: [33869-43-1] / [] MDL: MFCD30803399 Appearance: liquid Colour: clear Hazardous Classification: Flammable Liquid Storage Temp: 2-7°C Refrigerate logP: pKa: Tariff Code:...
1,251.00 € *
NEW
AS96740-G1 2,2-Dimethylbut-3-yn-1-ol 95+%
Catalog # AS96740 Formula: C6H10O Mass: 98.14 C.A.S. / related C.A.S: [65108-31-8] / [] MDL: MFCD14583019 Appearance: liquid Colour: clear Hazardous Classification: Flammable Liquid Storage Temp: 2-7°C Refrigerate logP: pKa: Dangerous...
From 1,043.00 € *
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AS96663-G1 1-(Trimethylsilyl)-1-propyne 95+%
Catalog # AS96663 Formula: C6H12Si Mass: 112.24 C.A.S. / related C.A.S: [6224-91-5] / [] MDL: MFCD00009271 Appearance: solid Colour: clear Hazardous Classification: Toxic Storage Temp: 2-7°C Refrigerate logP: pKa: Tariff Code: 29420000...
From 178.00 € *
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AS96613-G1 Ethyl pent-2-ynoate 97+%
Catalog # AS96613 Formula: C7H10O2 Mass: 126.15 C.A.S. / related C.A.S: [55314-57-3] / [] MDL: MFCD00015221 Appearance: liquid Colour: clear Hazardous Classification: Flammable Liquid Storage Temp: 2-7°C Refrigerate logP: pKa: Dangerous...
From 115.00 € *
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AS96616-G1 Methyl prop-2-ynoate 97+%
Catalog # AS96616 Formula: C4H4O2 Mass: 84.07 C.A.S. / related C.A.S: [922-67-8] / [] MDL: MFCD00008572 Appearance: liquid Colour: colorless - very pale yellow Hazardous Classification: Flammable Liquid Storage Temp: 2-7°C Refrigerate...
From 36.00 € *
NEW
AS96394-MG100 3-Ethynyloxetane 95+%
Catalog # AS96394 Formula: C5H6O Mass: 82.10 C.A.S. / related C.A.S: [1290541-38-6] / [] MDL: MFCD26516293 Appearance: liquid Colour: clear Hazardous Classification: Flammable Liquid Storage Temp: 2-7°C Refrigerate logP: pKa: Tariff...
From 353.00 € *
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AS96329-G1 4-Ethynyl-1-methylpiperidine 95+%
Catalog # AS96329 Formula: C8H13N Mass: 123.20 C.A.S. / related C.A.S: [91324-39-9] / [] MDL: MFCD13176213 Appearance: solid Colour: clear Hazardous Classification: Warning Storage Temp: 2-7°C Refrigerate logP: pKa: Tariff Code: 29333999...
From 1,112.00 € *
NEW
AS96285-MG100 4-Ethynyl-1,1-difluorocyclohexane 97+%
Catalog # AS96285 Formula: C8H10F2 Mass: 144.16 C.A.S. / related C.A.S: [1202245-66-6] / [] MDL: MFCD30802460 Appearance: solid Colour: clear Hazardous Classification: Warning Storage Temp: 2-7°C Refrigerate logP: pKa: Tariff Code:...
From 240.00 € *
NEW
AS96315-MG100 4-Ethyl-3-(2-{pyrazolo[1,5-a]pyrimidin-6-yl}eth...
Catalog # AS96315 Formula: C17H13N3O2 Mass: 291.30 C.A.S. / related C.A.S: [1429618-03-0] / [] MDL: MFCD30723474 Appearance: solid Colour: clear Hazardous Classification: Corrosive Storage Temp: 2-7°C Refrigerate logP: pKa: Tariff Code:...
From 288.00 € *
NEW
AS96242-MG100 3-Ethynylazetidine hydrochloride 95+%
Catalog # AS96242 Formula: C5H8ClN Mass: 117.58 C.A.S. / related C.A.S: [1426424-91-0] / [] MDL: MFCD18911000 Appearance: solid Colour: clear Hazardous Classification: Warning Storage Temp: 2-7°C Refrigerate logP: pKa: Tariff Code:...
From 282.00 € *
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